Relationships—including human-animal-microbial relations—are shaped by and through practices. Thus, practices form an essential component of our research whether we are observing them, participating in them, or inventing them. Antimicrobial resistance may be defined biologically, but it is produced by social practices, whether those practices be medical, technical, political, infrastructural or domestic. Our research projects taking AMR as their focus explore how AMR as a category and a phenomenon is produced in and by practices. We observe scientific practices that identify specific microbes as a particular entity and object to be worked upon, for example the Nordic development of an antidiarrheal vaccine in Benin and its trial with Finnish tourists. We are interested in the practices that shape past, present and future relations with microbes, including practices of working with and caring for soils, water, food, as well as bodies. As well as entities of documentation and analysis, practices are embodied in our methods: ethnography is a practice that can bring into rich focus the ways people perceive, live with and engage with microbes. Multispecies ethnography as a practice takes this further, engaging in methods that show the ways microbes and people live and become together. Our practices also include artistic and performative practices with microbes, and fermentation workshops.